ea0032p20 | Adrenal cortex | ECE2013
Rubin Beatrice
, Pezzani Raffaele
, Cicala Maria Verena
, Iacobone Maurizio
, Olivotto Andrea
, Fassina Ambrogio
, Manteri Franco
Background: Adrenocortical tumors (ACT) are classified as adenomas (ACA) or carcinomas (ACC). β-Catenin constitutive activation is a frequent alteration in benign and malignant ACT. E-cadherin was discovered as a protein associated with β-catenin which plays a crucial role in cadherin-mediated cell adhesion. N-cadherin seems to be involved in the development of malignant ACT, but information regarding expression of N-cadherin or E-cadherin in ACT is very limited....